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Pregnancy and toxoplasmosis

Pregnancy and toxoplasmosis

Question:

- I am 35 years old, I have 4 weeks of pregnancy and the analysis came out of the presence of toxoplasmosis antibodies. I repeated the analysis after 10 days to find out what limits (at another laboratory). I have a child of 3 years and 2 months. I looked at the analyzes and did not do this analysis at that time, my sister with 5 years younger did 16 years toxoplasmosis but it was treated, but I did not prevent this analysis. Now I'm scared and I even think I might have had the first child. What can you recommend, I will be able to keep the pregnancy, at the analyzes that I expect can be found if I have this disease for a long time? I should point out that as a child I had cats in the house I was sleeping with.

Answer:

Toxoplasmosis is a parasitic infection, being transmitted through contact with insufficiently prepared meat or from animals, especially cats.
Do not specify which type of antibody has been positive for toxoplasmosis: IgG, IgM or both. Anti-toxoplasma IgGs increase to 2-3 weeks from the time of infection, reaching a maximum level at 6-8 weeks, after which they decrease and remain at a basic level throughout life.
Thus, if IgG in toxoplasmosis is positive, but IgM remains negative, this means an infection that you have done in the past, which would not influence a current pregnancy; especially if the avidity index shows a distance of more than 3 months between the infection and the current pregnancy.

If IgM is positive, regardless of the value of IgG, this would mean an infection at the moment with this parasite. Treatment of toxoplasmosis is usually done with the combination of pyrimethamine, sulfadiazine, to which leucovorin is added and is long lasting.

Because toxoplasma is transmitted through the placenta to the fetus during pregnancy, which can cause serious disorders, I advise you to clarify the situation at this time either through a discussion with the obstetrician doctor or through an infectious disease consultation. Patients with a healthy immune system (immunocompetent) and who are not pregnant do not need treatment for toxoplasmosis.
Any symptoms that occur will be resolved without treatment, and a person who has had toxoplasmosis and has cured himself, can no longer be infected later (IgG provides protection in this regard).
Good health!